What are the differences between Tirzepatide and Semaglutide? +
Semaglutide mimics the action of a single glucagon-like peptide-1 (GLP-1), a hormone that increases insulin secretion, inhibits glucagon release, slows gastric emptying, and promotes satiety. Tirzepatide is a dual agonist that activates both the GLP-1 receptor and the glucose-dependent insulinotropic polypeptide (GIP) receptor. GIP is another incretin hormone that enhances insulin secretion post-meal and has complementary effects to GLP-1, potentially leading to greater weight loss and glycemic control. Tirzepatide has demonstrated even more impressive weight loss results in clinical trials, with participants losing an average of 15 to 20% of their body weight, and some achieving up to 25%.
What are the side effects? +
Common side effects include nausea, vomiting, diarrhea, and constipation. Most are mild and resolve as your body adjusts to the medication. Your clinician will review your full risk profile during consultation.
Who is not a candidate for weight loss injections? +
People with a history of pancreatitis, severe gastrointestinal disease, or medullary thyroid carcinoma (MTC) are generally not suitable candidates. The same applies to those with multiple endocrine neoplasia type 2 syndrome. These medications are also not recommended for women who are pregnant, planning to become pregnant, or breastfeeding.
How soon can I see results? +
Results vary from person to person, but many individuals begin to notice positive changes within a few weeks. Sustainable weight loss is a gradual process that requires ongoing commitment to a personalized plan. Our healthcare providers work closely with you to monitor progress and adjust your treatment plan as needed.
Do I need to follow a specific diet and exercise plan? +
Lifestyle changes can enhance your results. Our healthcare professionals will work with you to build a balanced diet and activity plan tailored to your needs, preferences, and health status. Sustainable weight loss comes from an approach that fits your life and supports long-term success.
How long do the weight loss treatments typically last? +
The duration of weight loss treatments varies depending on your individual goals, health status, and progress. Our healthcare professionals will work with you to establish a personalized timeline and provide ongoing guidance to help you achieve and maintain your desired results safely.
How often will I need to visit the clinic? +
The frequency of your clinic visits will depend on your personalized treatment plan and how you progress. Our healthcare team will work with you to create a schedule that fits your needs.
Can I combine weight loss injections with other treatments? +
It's important to discuss any other treatments or medications you are using with our healthcare professionals. We will ensure that your weight loss plan is safe and effective in conjunction with any other therapies.
What's the best practice for ending a GLP-1? +
We don't recommend stopping a GLP-1 cold once you've reached your goal weight. A lot of clinics skip this part — at SlimFit, we build a step-down protocol so your body adjusts gradually. The taper helps you avoid what some call 'revenge hunger,' the appetite rebound that drives weight regain when patients quit abruptly. Throughout the step-down, our team works with you on the nutrition habits and routines that keep you steady once the medication is fully out of your routine.
Will I gain the weight back after I stop a GLP-1? +
Not if you finish the protocol the right way. Weight regain after GLP-1s is real — but it's almost always tied to two things: stopping abruptly, and not having sustainable habits in place. Our program is built so you don't run into either. We taper your dose gradually as you approach maintenance, and we coach you on nutrition, movement, and the daily routines that keep results durable. The goal isn't just losing the weight; it's keeping it off long after the injections are done.